I develop statistical methods for random objects, including distributions, networks, functional data, and data on manifolds. My work focuses on Fréchet regression, causal inference, and machine learning in metric spaces.
I am an Assistant Professor in the School of Statistics at the University of Minnesota. I received my Ph.D. in Statistics from UC Davis in 2024, advised by Professor Hans-Georg Müller, and my B.S. in Statistics from the University of Science and Technology of China in 2019.
My research concerns statistical modeling and inference for random objects in metric spaces. Examples include probability distributions, networks, functional observations, compositions, and positive-definite matrices. I develop methods that account for their intrinsic geometry and recover familiar statistical procedures in Euclidean settings.
My current work centers on Fréchet regression, causal inference for structured outcomes, functional data analysis, and geometry-aware learning. Applications include longitudinal studies, neuroimaging and child development, economics and policy evaluation, and plant genomics. Before joining Minnesota, I was a postdoctoral scholar at UC Davis. I was also a research intern at Amazon in 2022.
Research
Fréchet regression
Regression methods for random objects in general metric spaces, including distributions, networks, and manifold-valued data.
Causal inference
Causal estimands and study designs for structured outcomes, including difference-in-differences, regression discontinuity, and synthetic control.
Statistical learning
Scalable methods for metric-space-valued data, including deep regression, boosting, transfer learning, and metric learning.
Functional data analysis
Models for longitudinal trajectories and sparsely observed functional data, with applications in biomedical and population studies.
Thrilled to share that our paper, End-to-End Deep Learning for Predicting Metric Space-Valued Outputs, has been accepted for publication in the Journal of Machine Learning Research. In this work, we introduce E2M, an end-to-end deep learning framework for predicting metric space-valued outputs via geometry-aware weighted Fréchet means.
research
Honored to share that our paper, Deep Fréchet Regression, has been selected as the discussion paper for the Journal of the American Statistical Association Theory & Methods Invited Session at the 2026 Joint Statistical Meetings. The invited session will take place on Monday, August 3rd (10:30am–12:20pm). As a discussion paper, our work will be accompanied by invited discussions and contributed comments, followed by a rejoinder.
research
I am delighted to share that two of our papers have been accepted for presentation at NeurIPS 2025.
Fréchet Geodesic Boosting: We introduce FGBoost, a gradient boosting framework designed to intrinsically model complex regression relationships with non-Euclidean outputs in geodesic metric spaces.
Wasserstein Transfer Learning: We propose a novel transfer learning framework for regression where outputs are probability distributions residing in the Wasserstein space.
research
Thrilled to announce that our paper, Deep Fréchet Regression, has been accepted for publication in the Journal of the American Statistical Association. In this work, we develop a deep learning framework for Fréchet regression, enabling flexible modeling of complex regression relationships where responses are random objects in general metric spaces.
Many modern applications involve predicting structured, non-Euclidean outputs such as probability distributions, networks, and symmetric positive-definite matrices. These outputs are naturally modeled as elements of general metric spaces, where classical regression techniques that rely on vector space structure no longer apply. We introduce E2M (End-to-End Metric regression), a deep learning framework for predicting metric space-valued outputs. E2M performs prediction via a weighted Fréchet means over training outputs, where the weights are learned by a neural network conditioned on the input. This construction provides a principled mechanism for geometry-aware prediction that avoids surrogate embeddings and restrictive parametric assumptions, while fully preserving the intrinsic geometry of the output space. We establish theoretical guarantees, including a universal approximation theorem that characterizes the expressive capacity of the model and a convergence analysis of the entropy-regularized training objective. Through extensive simulations involving probability distributions, networks, and symmetric positive-definite matrices, we show that E2M consistently achieves state-of-the-art performance, with its advantages becoming more pronounced at larger sample sizes. Applications to human mortality distributions and New York City taxi networks further demonstrate the flexibility and practical utility of the framework.
@article{zhou:25:7,title={End-to-End Deep Learning for Predicting Metric Space-Valued Outputs},author={Zhou, Yidong and Iao, Su I and M{\"u}ller, Hans-Georg},journal={Journal of Machine Learning Research},year={2026},volume={27},number={132},pages={1--38},}
Dynamic Modelling of Sparse Longitudinal Data and Functional Snippets with Stochastic Differential Equations
This paper received the 2024 IMS Hannan Graduate Student Travel Award.
Sparse functional/longitudinal data have attracted widespread interest due to the prevalence of such data in social and life sciences. A prominent scenario where such data are routinely encountered are accelerated longitudinal studies, where subjects are enrolled in the study at a random time and are only tracked for a short amount of time relative to the domain of interest. The statistical analysis of such functional snippets is challenging since information for far-off-diagonal regions of the covariance structure is missing. Our main methodological contribution is to address this challenge by bypassing covariance estimation and instead modelling the underlying process as the solution of a data-adaptive stochastic differential equation. Taking advantage of the interface between Gaussian functional data and stochastic differential equations makes it possible to efficiently reconstruct the target process by estimating its dynamic distribution. The proposed approach allows one to consistently recover forward sample paths from functional snippets at the subject level. We establish the existence and uniqueness of the solution to the proposed data-driven stochastic differential equation and derive rates of convergence for the corresponding estimators. The finite sample performance is demonstrated with simulation studies and functional snippets arising from a growth study and spinal bone mineral density data.
@article{zhou:24:3,title={Dynamic Modelling of Sparse Longitudinal Data and Functional Snippets with Stochastic Differential Equations},author={Zhou, Yidong and M{\"u}ller, Hans-Georg},journal={Journal of the Royal Statistical Society Series B: Statistical Methodology},volume={87},number={3},pages={833--849},year={2025},publisher={Oxford University Press UK},doi={10.1093/jrsssb/qkae116},}
This paper was selected as the discussion paper for the Journal of the American Statistical Association Theory & Methods Invited Session at the 2026 Joint Statistical Meetings and was also named a finalist for the 2025 Student Paper Award in the Nonparametric Statistics Section of the American Statistical Association.
Advancements in modern science have led to the increasing availability of non-Euclidean data in metric spaces. This paper addresses the challenge of modeling relationships between non-Euclidean responses and multivariate Euclidean predictors. We propose a flexible regression model capable of handling high-dimensional predictors without imposing parametric assumptions. Two primary challenges are addressed: the curse of dimensionality in nonparametric regression and the absence of linear structure in general metric spaces. The former is tackled using deep neural networks, while for the latter we demonstrate the feasibility of mapping the metric space where responses reside to a low-dimensional Euclidean space using manifold learning. We introduce a reverse mapping approach, employing local Féchet regression, to map the low-dimensional manifold representations back to objects in the original metric space. We develop a theoretical framework, investigating the convergence rate of deep neural networks under dependent sub-Gaussian noise with bias. The convergence rate of the proposed regression model is then obtained by expanding the scope of local Féchet regression to accommodate multivariate predictors in the presence of errors in predictors. Simulations and case studies show that the proposed model outperforms existing methods for non-Euclidean responses, focusing on the special cases of probability measures and networks.
@article{zhou:24:4,title={Deep Fr{\'e}chet Regression},author={Iao, Su I and Zhou, Yidong and M{\"u}ller, Hans-Georg},journal={Journal of the American Statistical Association},volume={120},number={551},pages={1437--1448},year={2025},doi={10.1080/01621459.2025.2507982},}
Gradient boosting has become a cornerstone of machine learning, enabling base learners such as decision trees to achieve exceptional predictive performance. While existing algorithms primarily handle scalar or Euclidean outputs, increasingly prevalent complex-structured data, such as distributions, networks, and manifold-valued responses, present challenges for traditional methods. Such non-Euclidean data lack algebraic structures such as addition, subtraction, or scalar multiplication required by standard gradient boosting frameworks. To address these challenges, we introduce \textitFréchet geodesic boosting (FGBoost), a novel approach tailored for responses residing in geodesic metric spaces. FGBoost leverages geodesics as proxies for residuals and constructs ensembles in a way that respects the intrinsic geometry of the response space. Through theoretical analysis, extensive simulations, and real-world applications, we demonstrate the strong performance and adaptability of FGBoost, showcasing its potential for modeling complex data.
@inproceedings{zhou:25,title={Fr{\'e}chet Geodesic Boosting},author={Zhou, Yidong and Iao, Su I and M{\"u}ller, Hans-Georg},booktitle={Advances in Neural Information Processing Systems},editor={Belgrave, D. and Zhang, C. and Montoya, L and Lin, H.T. and Chen, N. and Ghassemi, M. and Koniusz, P. and Pascanu, R.},volume={38},pages={80009--80038},year={2025},doi={10.52202/085713-2414},}